PF-06647263 Antibody
PF-06647263 is an antibody-drug conjugate (ADC) targeting EFNA4 and conjugated to calicheamicin. It demonstrates potent anti-tumor activity, inducing significant regression in triple-negative breast cancer (TNBC) xenograft models, supporting its investigation for oncology research in both in vitro and in vivo applications.
Product Specifications
Product Name Alternative
PF06647263, anti-EFNA4-ADC
Target
Apoptosis, DNA Alkylator/Crosslinker, Antibiotic
Clonality
Recombinant
Conjugation
Unconjugated
Field of Research
Cell Biology, Infectious Disease & Virology, Molecular Biology
Concentration
4.56 mg/mL
Purity
99.31% (May vary between batches)
Molecular Weight
147.14 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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