PLAA Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Phospholipase A2 activating protein
Gene Aliases
DOA1; DOA1 homolog; NDMSBA; phospholipase A-2-activating protein; PLA2P; PLAP.
Gene ID
9373
Accession Number
NP_001026859.1
Reactivity
Human
Immunogen
Range: Glu162 - Ala312
Target
Plays a role in protein ubiquitination, sorting and degradation through its association with VCP (PubMed:27753622) . Involved in ubiquitin-mediated membrane proteins trafficking to late endosomes in an ESCRT-dependent manner, and hence plays a role in synaptic vesicle recycling (By similarity) . May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes (PubMed:27753622) . Plays a role in cerebellar Purkinje cell development (By similarity) . Positively regulates cytosolic and calcium-independent phospholipase A2 activities in a tumor necrosis factor alpha (TNF-alpha) - or lipopolysaccharide (LPS) -dependent manner, and hence prostaglandin E2 biosynthesis (PubMed:18291623, PubMed:28007986) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
87 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against PLAA. It has been selected for its ability to recognize PLAA in immunohistochemical staining and western blotting.
NCBI Gene Symbol
PLAA
Host or Source
Rabbit
Protein Name
Phospholipase A-2-activating protein
Gene Name URL
PLAA
Nucleotide Accession Number
NM_001031689
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