What is the catalog number for PODXL Antibody?

The catalog number for PODXL Antibody is OACD06347-1ML.

What sizes are available for PODXL Antibody?

PODXL Antibody is available in the following size(s): 1 mL.

Is PODXL Antibody in stock?

PODXL Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

PODXL Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Podocalyxin-like

Gene Aliases

AW121214; Ly10; Ly102; P; PC; Pclp1; PCLP-1; Pod; podo; podocalyxin; podocalyxin-like protein 1; Podxl1.

Gene ID

27205

Accession Number

NP_038751.2

Reactivity

Human|Mouse|Rat

Immunogen

Recombinant PODXL (Pro171~Ser404) expressed in E.coli

Target

Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin-dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial polarization and the apical lumen formation during renal tubulogenesis. Plays a role in cancer development and aggressiveness by inducing cell migration and invasion through its interaction with the actin-binding protein EZR. Affects EZR-dependent signaling events, leading to increased activities of the MAPK and PI3K pathways in cancer cells.

Clonality

Polyclonal

Type

Polyclonal Antibody

Source

Polyclonal antibody preparation

Applications

Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

Purification

Affinity Purified; Protein A Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

Reconstitution

2°C to 8°C|-20°C

Fragment

IgG

Specificity

The antibody is a rabbit polyclonal antibody raised against PCX. It has been selected for its ability to recognize PCX in immunohistochemical staining and western blotting.