OSTN Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Osteocrin
Gene Aliases
Mus; musclin; Os; Ostc; osteocrin.
Gene ID
239790
Accession Number
NP_932780.1
Reactivity
Mouse
Immunogen
Recombinant OSTN (VPhe26~Gly130) expressed in E.coli.
Target
Hormone that acts as a ligand for natriuretic peptide receptor NPR3/NPR-C and promotes bone growth and physical endurance in muscle. Acts as a regulator of osteoblast differentiation and bone growth by binding to natriuretic peptide receptor NPR3/NPR-C, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production (PubMed:14523025, PubMed:17951249) . Required to enhance physical endurance: induced following physical exercise in muscle and promotes cGMP production, probably by interacting with NPR3/NPR-C (PubMed:26668395) . May act as an autocrine and paracrine factor linked to glucose metabolism in skeletal muscle (PubMed:15044443) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Source
Polyclonal antibody preparation
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
14 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against OSTN. It has been selected for its ability to recognize OSTN in immunohistochemical staining and western blotting.
NCBI Gene Symbol
Ostn
Host or Source
Rabbit
Protein Name
Osteocrin
Gene Name URL
Ostn
Nucleotide Accession Number
NM_198112
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