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OSTN Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Osteocrin

Gene Aliases

Mus; musclin; Os; Ostc; osteocrin.

Gene ID

239790

Accession Number

NP_932780.1

Reactivity

Mouse

Immunogen

Recombinant OSTN (VPhe26~Gly130) expressed in E.coli.

Target

Hormone that acts as a ligand for natriuretic peptide receptor NPR3/NPR-C and promotes bone growth and physical endurance in muscle. Acts as a regulator of osteoblast differentiation and bone growth by binding to natriuretic peptide receptor NPR3/NPR-C, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production (PubMed:14523025, PubMed:17951249) . Required to enhance physical endurance: induced following physical exercise in muscle and promotes cGMP production, probably by interacting with NPR3/NPR-C (PubMed:26668395) . May act as an autocrine and paracrine factor linked to glucose metabolism in skeletal muscle (PubMed:15044443) .

Clonality

Polyclonal

Type

Polyclonal Antibody

Source

Polyclonal antibody preparation

Applications

Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

Purification

Affinity Purified; Protein A Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Reconstitution

2°C to 8°C|-20°C

Molecular Weight

14 kDa

Fragment

IgG

Specificity

The antibody is a rabbit polyclonal antibody raised against OSTN. It has been selected for its ability to recognize OSTN in immunohistochemical staining and western blotting.

NCBI Gene Symbol

Ostn

Host or Source

Rabbit

Protein Name

Osteocrin

Gene Name URL

Ostn

Nucleotide Accession Number

NM_198112

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