What is the catalog number for MBD2 Antibody?

The catalog number for MBD2 Antibody is OACD05462-1ML.

What sizes are available for MBD2 Antibody?

MBD2 Antibody is available in the following size(s): 1 mL.

Is MBD2 Antibody in stock?

MBD2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

MBD2 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Methyl-CpG binding domain protein 2

Gene Aliases

Demethylase; DMTase; methyl-CpG-binding domain protein 2; Methyl-CpG-binding protein MBD2; NY-CO-41.

Gene ID

8932

Accession Number

NP_003918.1

Reactivity

Human|Mouse|Rat

Immunogen

Range: Glu145 - Ala411

Target

Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

Purification

Affinity Purified; Protein A Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Reconstitution

2°C to 8°C|-20°C

Molecular Weight

32 kDa

Fragment

IgG

Specificity

The antibody is a rabbit polyclonal antibody raised against MBD2. It has been selected for its ability to recognize MBD2 in immunohistochemical staining and western blotting.