MAP3K1 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Mitogen-activated protein kinase kinase kinase 1
Gene Aliases
MAP/ERK kinase kinase 1; MAPK/ERK kinase kinase 1; MAPKKK1; MEK kinase 1; MEKK; MEKK 1; MEKK1; mitogen-activated protein kinase kinase kinase 1; mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase; SRXY6.
Gene ID
4214
Accession Number
NP_005912.1
Reactivity
Human|Mouse
Immunogen
Range: Ile1307 - Arg1509
Target
Component of a protein kinase signal transduction cascade (PubMed:9808624) . Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4 (PubMed:9808624) . May phosphorylate the MAPK8/JNK1 kinase (PubMed:17761173) . Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway (PubMed:9808624) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
164 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against MAP3K1. It has been selected for its ability to recognize MAP3K1 in immunohistochemical staining and western blotting.
NCBI Gene Symbol
MAP3K1
Host or Source
Rabbit
Protein Name
Mitogen-activated protein kinase kinase kinase 1
Gene Name URL
MAP3K1
Nucleotide Accession Number
NM_005921
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