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MAEA Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Macrophage erythroblast attacher, E3 ubiquitin ligase

Gene Aliases

Cell proliferation-inducing gene 5 protein; E3 ubiquitin-protein transferase MAEA; EMLP; EMP; erythroblast macrophage protein; GID complex subunit 9, FYV10 homolog; GID9; HLC-10; human lung cancer oncogene 10 protein; lung cancer-related protein 10; P44EMLP; PIG5.

Gene ID

10296

Accession Number

NP_001017405.1

Reactivity

Human|Mouse|Rat

Immunogen

Range: Cys136 - Pro379

Target

Plays a role in erythroblast enucleation and in the development of the mature macrophages. Mediates the attachment of erythroid cell to mature macrophages, in correlation with the presence of MAEA at cell surface of mature macrophages; This MAEA-mediated contact inhibits erythroid cells apoptosis. Participates in erythroblastic island formation, which is the functional unit of definitive erythropoiesis. Associates with F-actin to regulate actin distribution in erythroblasts and macrophages. May contribute to nuclear architecture and cells division events.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

Purification

Affinity Purified; Protein A Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

Reconstitution

2°C to 8°C|-20°C

Molecular Weight

27 kDa

Fragment

IgG

Specificity

The antibody is a rabbit polyclonal antibody raised against MAEA. It has been selected for its ability to recognize MAEA in immunohistochemical staining and western blotting.

NCBI Gene Symbol

MAEA

Host or Source

Rabbit

Protein Name

Macrophage erythroblast attacher

Gene Name URL

MAEA

Nucleotide Accession Number

NM_001017405

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