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LRP1 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Low density lipoprotein receptor-related protein 1

Gene Aliases

A2; A2mr; AI316852; alpha 2-macroglobulin receptor; Alpha-2-macroglobulin receptor; b2b1554C; b2b1554Clo; CD91; lipoprotein receptor-related protein; Lrp; LRP-1; prolow-density lipoprotein receptor-related protein 1.

Gene ID

16971

Accession Number

NP_032538.2

Reactivity

Human|Mouse|Rat

Immunogen

Range: Lys337 - Ala426

Target

Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development (PubMed:1423604) . Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission. Acts as an alpha-2-macroglobulin receptor (By similarity) .

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

Purification

Affinity Purified; Protein A Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

Reconstitution

2°C to 8°C|-20°C

Molecular Weight

505 kDa

Fragment

IgG

Specificity

The antibody is a rabbit polyclonal antibody raised against LRP1. It has been selected for its ability to recognize LRP1 in immunohistochemical staining and western blotting.

NCBI Gene Symbol

Lrp1

Host or Source

Rabbit

Protein Name

Prolow-density lipoprotein receptor-related protein 1

Gene Name URL

Lrp1

Nucleotide Accession Number

NM_008512

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