LPCAT1 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Lysophosphatidylcholine acyltransferase 1

Gene Aliases

1-acylglycerol-3-phosphate O-acyltransferase;1-acylglycerophosphocholine O-acyltransferase;1-alkenylglycerophosphocholine O-acyltransferase;1-alkylglycerophosphocholine O-acetyltransferase;2900035H07Rik; acetyl-CoA:lyso-PAF acetyltransferase; acetyl-CoA:lyso-platelet-activating factor acetyltransferase; acyltransferase-like 2; Ayt; Aytl2; BB137372; BC005662; C87117; LP; LPC acyltransferase 1; LPCAT; LPCAT-1; lyso-PAF acetyltransferase; lysoPAFAT; lysoPC acyltransferase 1; lysophosphatidylcholine acyltransferase 1; mLPCAT1; rd1; rd11.

Gene ID

210992

Accession Number

NP_663351.3

Reactivity

Human|Mouse|Rat

Immunogen

Range: Ala301 - Cys514

Target

Possesses both acyltransferase and acetyltransferase activities (PubMed:16704971) . Activity is calcium-independent (PubMed:18285344) . Mediates the conversion of 1-acyl-sn-glycero-3-phosphocholine (LPC) into phosphatidylcholine (PC) (PubMed:16704971, PubMed:18156367) . Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively (PubMed:16704971, PubMed:18285344) . May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology (PubMed:16704971) . Involved in the regulation of lipid droplet number and size (By similarity) .

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

Purification

Affinity Purified; Protein A Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

Reconstitution

2°C to 8°C|-20°C

Molecular Weight

37 kDa

Fragment

IgG

Specificity

The antibody is a rabbit polyclonal antibody raised against LPCAT1. It has been selected for its ability to recognize LPCAT1 in immunohistochemical staining and western blotting.