WWC1 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
WW, C2 and coiled-coil domain containing 1
Gene Aliases
AA408228; AU017197; BC037006; Ki; Kibra; kidney and brain protein; protein KIBRA; protein WWC1; WW domain-containing protein 1.
Gene ID
211652
Accession Number
NP_740749.1
Reactivity
Human|Mouse|Rat
Immunogen
Range: Glu847 - Met1094
Target
Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with NF2 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. Acts as a transcriptional coactivator of ESR1 which plays an essential role in DYNLL1-mediated ESR1 transactivation. Regulates collagen-stimulated activation of the ERK/MAPK cascade. Modulates directional migration of podocytes. Acts as a substrate for PRKCZ and may be associated with memory performance (By similarity) . Regulates collagen-stimulated activation of the ERK/MAPK cascade.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.43 mg/ml
Format
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
124 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against KIBRA. It has been selected for its ability to recognize KIBRA in immunohistochemical staining and western blotting.
NCBI Gene Symbol
Wwc1
Host or Source
Rabbit
Protein Name
Protein KIBRA
Gene Name URL
Wwc1
Nucleotide Accession Number
NM_170779
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog