PLA2G6 Antibody
Product Specifications
Gene Name
Phospholipase A2, group VI
Gene Aliases
2-lysophosphatidylcholine acylhydrolase;85 kDa calcium-independent phospholipase A2;85/88 kDa calcium-independent phospholipase A2; BB112799; caI-PLA2; group VI phospholipase A2; GVI PLA2; i; intracellular membrane-associated calcium-independent phospholipase A2 beta; iPLA; iPLA (2) beta; iPLA2; iPLA2beta; iPLA2-beta; palmitoyl-CoA hydrolase; patatin-like phospholipase domain-containing protein 9; PNPLA9.
Gene ID
53357
Accession Number
NP_001185952.1
Reactivity
Human|Mouse|Rat
Immunogen
Range: Leu481 - Val702
Target
Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F-actin polymerization at the pseudopods (By similarity) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.22 mg/ml
Format
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
84 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against iPLA2. It has been selected for its ability to recognize iPLA2 in immunohistochemical staining and western blotting.
NCBI Gene Symbol
Pla2g6
Host or Source
Rabbit
Protein Name
85/88 kDa calcium-independent phospholipase A2
Gene Name URL
Pla2g6
CAS Number
9007-83-4
Nucleotide Accession Number
NM_001199023
Curated Selection
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