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CD101 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

CD101 antigen

Gene Aliases

EWI immunoglobulin subfamily member EWI-101; EWI-101; glu-Trp-Ile EWI motif-containing protein 101; Gm1016; Gm734; Igs; Igsf2; immunoglobulin superfamily member 2; immunoglobulin superfamily, member 2; leukocyte surface protein.

Gene ID

630146

Accession Number

NP_001161378.1

Reactivity

Mouse

Immunogen

Range: Leu302 - Thr531

Target

Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells (By similarity) .

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

Purification

Affinity Purified; Protein A Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

Reconstitution

2°C to 8°C|-20°C

Molecular Weight

114 kDa

Fragment

IgG

Specificity

The antibody is a rabbit polyclonal antibody raised against IGSF2. It has been selected for its ability to recognize IGSF2 in immunohistochemical staining and western blotting.

NCBI Gene Symbol

Cd101

Host or Source

Rabbit

Protein Name

Immunoglobulin superfamily member 2

Gene Name URL

Cd101

Nucleotide Accession Number

NM_001167906

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