CD101 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
CD101 molecule
Gene Aliases
Cell surface glycoprotein V7; EWI-101; glu-Trp-Ile EWI motif-containing protein 101; IGSF2; immunoglobulin superfamily member 2; leukocyte surface protein; V7.
Gene ID
9398
Accession Number
NP_001243035.1
Reactivity
Human|Porcine
Immunogen
Range: Ala566 - Leu784
Target
Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells. May be a marker of CD4 (+) CD56 (+) leukemic tumor cells.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunohistochemistry|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
115 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against IGSF2. It has been selected for its ability to recognize IGSF2 in immunohistochemical staining and western blotting.
NCBI Gene Symbol
CD101
Host or Source
Rabbit
Protein Name
Immunoglobulin superfamily member 2
Gene Name URL
CD101
Nucleotide Accession Number
NM_001256106
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