What is the catalog number for EPAS1 Antibody?

The catalog number for EPAS1 Antibody is OACD04185-1ML.

What sizes are available for EPAS1 Antibody?

EPAS1 Antibody is available in the following size(s): 1 mL.

Is EPAS1 Antibody in stock?

EPAS1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

EPAS1 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Endothelial PAS domain protein 1

Gene Aliases

Endothelial PAS domain-containing protein 1; EPAS-1; HIF2 alpha; HIF-2 alpha; Hif2a; HIF2-alpha; HIF-2-alpha; HLF; hypoxia inducible factor 2, alpha subunit; hypoxia inducible factor 2a; hypoxia-inducible factor 2-alpha.

Gene ID

29452

Accession Number

NP_075578.1

Reactivity

Human|Mouse|Rat

Immunogen

Range: Arg24 - Glu348

Target

Transcription factor involved in the induction of oxygen regulated genes. Heterodimerizes with ARNT; heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters (By similarity) . Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation requires recruitment of transcriptional coactivators such as CREBBP and probably EP300. Interaction with redox regulatory protein APEX seems to activate CTAD (By similarity) .

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

Purification

Affinity Purified; Protein A Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

Reconstitution

2°C to 8°C|-20°C

Molecular Weight

97 kDa

Fragment

IgG

Specificity

The antibody is a rabbit polyclonal antibody raised against HIF2a. It has been selected for its ability to recognize HIF2a in immunohistochemical staining and western blotting.