HBEGF Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Heparin binding EGF like growth factor

Gene Aliases

Diphtheria toxin receptor (heparin-binding EGF-like growth factor) ; diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor) ; DTR; DTS; DTSF; HEGFL; heparin-binding epidermal growth factor; proheparin-binding EGF-like growth factor.

Gene ID

1839

Accession Number

NP_001936.1

Reactivity

Human|Porcine

Immunogen

Range: Val21 - Thr160

Target

Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Immunohistochemistry|Western blot

Purification

Affinity Purified; Protein A Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Reconstitution

2°C to 8°C|-20°C

Molecular Weight

23 kDa

Fragment

IgG

Specificity

The antibody is a rabbit polyclonal antibody raised against HBEGF. It has been selected for its ability to recognize HBEGF in immunohistochemical staining and western blotting.