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GCKR Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Glucokinase regulator

Gene Aliases

GLRE; glucokinase (hexokinase 4) regulator; glucokinase regulatory protein.

Gene ID

25658

Accession Number

NP_037252.1

Reactivity

Human|Mouse|Rat

Immunogen

Range: Val320 - Lys499

Target

Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

Purification

Affinity Purified; Protein A Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

Reconstitution

2°C to 8°C|-20°C

Molecular Weight

69 kDa

Fragment

IgG

Specificity

The antibody is a rabbit polyclonal antibody raised against GKRP. It has been selected for its ability to recognize GKRP in immunohistochemical staining and western blotting.

NCBI Gene Symbol

Gckr

Host or Source

Mouse

Protein Name

Glucokinase regulatory protein

Gene Name URL

Gckr

Nucleotide Accession Number

NM_013120

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