GGT1 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Gamma-glutamyltransferase 1
Gene Aliases
CD224; D22S672; D22S732; Gamma-glutamyltransferase 1; gamma-glutamyltranspeptidase 1; GGT; GGT 1; GGTD; glutathione hydrolase 1 proenzyme; GTG; leukotriene-C4 hydrolase; testicular tissue protein Li 73.
Gene ID
2678
Accession Number
NP_001275762.1
Reactivity
Human|Mouse|Porcine
Immunogen
Range: Ser122 - Ser299
Target
Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates, and other gamma-glutamyl compounds. The metabolism of glutathione releases free glutamate and the dipeptide cysteinyl-glycine, which is hydrolyzed to cysteine and glycine by dipeptidases. In the presence of high concentrations of dipeptides and some amino acids, can also catalyze a transpeptidation reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level. It is part of the cell antioxidant defense mechanism. Isoform 3 seems to be inactive.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
24 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against gGT1. It has been selected for its ability to recognize gGT1 in immunohistochemical staining and western blotting.
NCBI Gene Symbol
GGT1
Host or Source
Rabbit
Protein Name
Glutathione hydrolase 1 proenzyme
Gene Name URL
GGT1
Nucleotide Accession Number
NM_001288833
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog