FKBP4 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

FKBP prolyl isomerase 4

Gene Aliases

51 kDa FK506-binding protein;52 kDa FK506-binding protein;59 kDa immunophilin; FK506 binding protein 4, 59kDa; FK506-binding protein 4; FKBP51; FKBP52; FKBP59; HBI; HSP binding immunophilin; Hsp56; HSP-binding immunophilin; Immunophilin FKBP52; p52; peptidylprolyl cis-trans isomerase; peptidyl-prolyl cis-trans isomerase FKBP4; PPIase; rotamase; T-cell FK506-binding protein, 59kD.

Gene ID

2288

Accession Number

NP_002005.1

Reactivity

Human|Porcine

Immunogen

Range: Thr2 - Ala459

Target

Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90) . May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May have a protective role against oxidative stress in mitochondria.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Immunohistochemistry|Western blot

Purification

Affinity Purified; Protein A Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Reconstitution

2°C to 8°C|-20°C

Molecular Weight

52 kDa

Fragment

IgG

Specificity

The antibody is a rabbit polyclonal antibody raised against FKBP4. It has been selected for its ability to recognize FKBP4 in immunohistochemical staining and western blotting.