IL1F5 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Interleukin 36 receptor antagonist
Gene Aliases
AI413231; FIL1d; Fil1delta; If36rn; IL1; IL-1; IL-1 delta; Il1f5; IL-1F5; IL1H; Il-1h3; Il1hy1; IL-1HY1; IL-1L1; IL-36Ra; interleukin 1 family, member 5 (delta) ; interleukin 1 receptor antagonist homolog 1; interleukin-1 delta; interleukin-1 family member 5; interleukin-1 homolog 3; interleukin-1 HY1; interleukin-1-like protein 1; interleukin-36 receptor antagonist protein.
Gene ID
54450
Accession Number
NP_001139559.1
Reactivity
Mouse
Immunogen
Range: Met1 - Asp156
Target
Inhibits the activity of interleukin-36 (IL36A, IL36B and IL36G) by binding to receptor IL1RL2/IL-36R and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens. May activate an anti-inflammatory signaling pathway by recruiting SIGIRR.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
17 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against FIL1d. It has been selected for its ability to recognize FIL1d in immunohistochemical staining and western blotting.
NCBI Gene Symbol
Il36rn
Host or Source
Rabbit
Protein Name
Interleukin-36 receptor antagonist protein
Gene Name URL
Il36rn
Nucleotide Accession Number
NM_001146087
Frequently Asked Questions
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