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IL1F5 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Interleukin 36 receptor antagonist

Gene Aliases

AI413231; FIL1d; Fil1delta; If36rn; IL1; IL-1; IL-1 delta; Il1f5; IL-1F5; IL1H; Il-1h3; Il1hy1; IL-1HY1; IL-1L1; IL-36Ra; interleukin 1 family, member 5 (delta) ; interleukin 1 receptor antagonist homolog 1; interleukin-1 delta; interleukin-1 family member 5; interleukin-1 homolog 3; interleukin-1 HY1; interleukin-1-like protein 1; interleukin-36 receptor antagonist protein.

Gene ID

54450

Accession Number

NP_001139559.1

Reactivity

Mouse

Immunogen

Range: Met1 - Asp156

Target

Inhibits the activity of interleukin-36 (IL36A, IL36B and IL36G) by binding to receptor IL1RL2/IL-36R and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens. May activate an anti-inflammatory signaling pathway by recruiting SIGIRR.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

Purification

Affinity Purified; Protein A Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Reconstitution

2°C to 8°C|-20°C

Molecular Weight

17 kDa

Fragment

IgG

Specificity

The antibody is a rabbit polyclonal antibody raised against FIL1d. It has been selected for its ability to recognize FIL1d in immunohistochemical staining and western blotting.

NCBI Gene Symbol

Il36rn

Host or Source

Rabbit

Protein Name

Interleukin-36 receptor antagonist protein

Gene Name URL

Il36rn

Nucleotide Accession Number

NM_001146087

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