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FGG Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Fibrinogen gamma chain

Gene Aliases

3010002H13Rik; AI256424; fibrinogen gamma chain; fibrinogen, gamma polypeptide.

Gene ID

99571

Accession Number

NP_598623.1

Reactivity

Human|Mouse|Rat

Immunogen

Range: Val168 - Lys405

Target

Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix (By similarity) . Fibrin has a major function in hemostasis as one of the primary components of blood clots (By similarity) . In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization (By similarity) . Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo (By similarity) . Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway (PubMed:19332769) . Maternal fibrinogen is essential for successful pregnancy (By similarity) . Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage (By similarity) . May also facilitate the immune response via both innate and T-cell mediated pathways (By similarity) .

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

Purification

Affinity Purified; Protein A Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Reconstitution

2°C to 8°C|-20°C

Molecular Weight

49 kDa

Fragment

IgG

Specificity

The antibody is a rabbit polyclonal antibody raised against FGg. It has been selected for its ability to recognize FGg in immunohistochemical staining and western blotting.

NCBI Gene Symbol

Fgg

Host or Source

Rabbit

Protein Name

Fibrinogen gamma chain

Gene Name URL

Fgg

Nucleotide Accession Number

NM_133862

Frequently Asked Questions

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