FCNA Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Ficolin A
Gene Aliases
Collagen/fibrinogen domain-containing protein 1; Fcn; Fcn1; ficolin-1; Ficolin-A; ficolin-alpha; M-ficolin.
Gene ID
14133
Accession Number
NP_032021.1
Reactivity
Mouse
Immunogen
Range: Arg25 - Gly317
Target
Extracellular lectin functioning as a pattern-recognition receptor in innate immunity. Binds the sugar moieties of pathogen-associated molecular patterns (PAMPs) displayed on microbes and activates the lectin pathway of the complement system. May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8. Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage (By similarity) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
Varies by lot. See vial for concentration.
Format
Liquid// 0.01M PBS (pH 7.4) containing 0.05% Proclin300 and 50% glycerol
Reconstitution
Store at 4° C for frequent use. Aliquot and store at -20° C for 12 months. Avoid repeated freeze/thaw cycles.
Molecular Weight
36 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against FCN1. It has been selected for its ability to recognize FCN1 in immunohistochemical staining and western blotting.
NCBI Gene Symbol
Fcna
Host or Source
Rabbit
Protein Name
Ficolin-1
Gene Name URL
Fcna
Nucleotide Accession Number
NM_007995
Frequently Asked Questions
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