FBXL3 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
F-box and leucine-rich repeat protein 3
Gene Aliases
AU041772; AW212966; FBK; Fbl; Fbl3a; F-box and leucine-rich repeat protein 3a; F-box/LRR-repeat protein 3; F-box/LRR-repeat protein 3A; Fbxl; Fbxl3a; Ov; Ovtm; Pla; Play68; protein after-hours; protein overtime.
Gene ID
50789
Accession Number
NP_056637.1
Reactivity
Human|Mouse|Rat
Immunogen
Range: Met1 - Tyr292
Target
Substrate-recognition component of the SCF (FBXL3) E3 ubiquitin ligase complex involved in circadian rhythm function. Plays a key role in the maintenance of both the speed and the robustness of the circadian clock oscillation. The SCF (FBXL3) complex mainly acts in the nucleus and mediates ubiquitination and subsequent degradation of CRY1 and CRY2. Activity of the SCF (FBXL3) complex is counteracted by the SCF (FBXL21) complex.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
43 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against FBXL3. It has been selected for its ability to recognize FBXL3 in immunohistochemical staining and western blotting.
NCBI Gene Symbol
Fbxl3
Host or Source
Rabbit
Protein Name
F-box/LRR-repeat protein 3
Gene Name URL
Fbxl3
Nucleotide Accession Number
NM_015822
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