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FBXL3 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

F-box and leucine-rich repeat protein 3

Gene Aliases

AU041772; AW212966; FBK; Fbl; Fbl3a; F-box and leucine-rich repeat protein 3a; F-box/LRR-repeat protein 3; F-box/LRR-repeat protein 3A; Fbxl; Fbxl3a; Ov; Ovtm; Pla; Play68; protein after-hours; protein overtime.

Gene ID

50789

Accession Number

NP_056637.1

Reactivity

Human|Mouse|Rat

Immunogen

Range: Met1 - Tyr292

Target

Substrate-recognition component of the SCF (FBXL3) E3 ubiquitin ligase complex involved in circadian rhythm function. Plays a key role in the maintenance of both the speed and the robustness of the circadian clock oscillation. The SCF (FBXL3) complex mainly acts in the nucleus and mediates ubiquitination and subsequent degradation of CRY1 and CRY2. Activity of the SCF (FBXL3) complex is counteracted by the SCF (FBXL21) complex.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

Purification

Affinity Purified; Protein A Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

Reconstitution

2°C to 8°C|-20°C

Molecular Weight

43 kDa

Fragment

IgG

Specificity

The antibody is a rabbit polyclonal antibody raised against FBXL3. It has been selected for its ability to recognize FBXL3 in immunohistochemical staining and western blotting.

NCBI Gene Symbol

Fbxl3

Host or Source

Rabbit

Protein Name

F-box/LRR-repeat protein 3

Gene Name URL

Fbxl3

Nucleotide Accession Number

NM_015822

Frequently Asked Questions

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