FBLN5 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Fibulin 5

Gene Aliases

ADCL2; ARCL1A; ARMD3; DANCE; developmental arteries and neural crest EGF-like protein; embryonic vascular EGF-like repeat-containing protein; EVEC; FIBL-5; fibulin-5; HNARMD; testis tissue sperm-binding protein Li 75n; UP50; urine p50 protein.

Gene ID

10516

Accession Number

NP_006320.2

Reactivity

Human|Mouse|Rat

Immunogen

Range: Leu99 - Cys205

Target

Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN (PubMed:18185537) . Stabilizes and organizes elastic fibers in the skin, lung and vasculature (By similarity) . Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling (PubMed:10428823) . May act as an adapter that mediates the interaction between FBN1 and ELN (PubMed:17255108) .

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

Purification

Affinity Purified; Protein A Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Reconstitution

2°C to 8°C|-20°C

Molecular Weight

50 kDa

Fragment

IgG

Specificity

The antibody is a rabbit polyclonal antibody raised against FBLN5. It has been selected for its ability to recognize FBLN5 in immunohistochemical staining and western blotting.