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TSC22D3 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

TSC22 domain family member 3

Gene Aliases

Delta sleep-inducing peptide immunoreactor; DIP; DSIPI; DSIP-immunoreactive leucine zipper protein; DSIP-immunoreactive peptide; GILZ; glucocorticoid-induced leucine zipper protein; TSC22 domain family protein 3; TSC-22 related protein; TSC-22-like protein; TSC-22R; TSC-22-related protein.

Gene ID

1831

Accession Number

NP_001015881.1

Reactivity

Human|Mouse|Rat

Immunogen

Range: Met1 - Val134

Target

Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities (By similarity) . Isoform 1 inhibits myogenic differentiation and mediates anti-myogenic effects of glucocorticoids by binding and regulating MYOD1 and HDAC1 transcriptional activity resulting in reduced expression of MYOG (By similarity) .

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunohistochemistry|Immunohistochemistry-Frozen|Immunohistochemistry-Paraffin|Western blot

Purification

Affinity Purified; Protein A Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Reconstitution

2°C to 8°C|-20°C

Molecular Weight

13 kDa

Fragment

IgG

Specificity

The antibody is a rabbit polyclonal antibody raised against dSIP. It has been selected for its ability to recognize dSIP in immunohistochemical staining and western blotting.

NCBI Gene Symbol

TSC22D3

Host or Source

Rabbit

Protein Name

TSC22 domain family protein 3

Gene Name URL

TSC22D3

Nucleotide Accession Number

NM_001015881

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