What is the catalog number for CXADR Antibody?

The catalog number for CXADR Antibody is OACD02893-100UL.

What sizes are available for CXADR Antibody?

CXADR Antibody is available in the following size(s): 100 µL.

Is CXADR Antibody in stock?

CXADR Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

CXADR Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

CXADR Ig-like cell adhesion molecule

Gene Aliases

46 kD coxsackievirus and adenovirus receptor (CAR) protein; CAR; CAR4/6; coxsackie virus and adenovirus receptor; coxsackievirus and adenovirus receptor; coxsackievirus B-adenovirus receptor; CVB3-binding protein; HCAR; HCVADR.

Gene ID

1525

Accession Number

NP_001193992.1

Reactivity

Human|Mouse|Rat

Immunogen

Range: Leu20 - Val229

Target

Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified; Protein A Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Reconstitution

2°C to 8°C|-20°C

Molecular Weight

10 kDa

Fragment

IgG

Specificity

The antibody is a rabbit polyclonal antibody raised against CXADR. It has been selected for its ability to recognize CXADR in immunohistochemical staining and western blotting.