C4A Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Complement C4A (Rodgers blood group) |complement C4B (Chido blood group)
Gene Aliases
Acidic C4; acidic complement C4; basic complement C4; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3; C4; C4A anaphylatoxin; C4A2; C4A3; C4A4; C4A6; C4AD; C4B_2; C4B1; C4B12; C4B2; C4B3; C4B5; C4BD; C4F; C4S; CH; Chido form of C4; CO4; complement C4-A; complement C4-B; complement C4B1a; complement component 4A (Rodgers blood group) ; complement component 4B (Chido blood group) ; CPAMD2; CPAMD3; MHC class III region complement; RG; Rodgers form of C4.
Gene ID
720|721
Accession Number
NP_001002029.3
Reactivity
Human
Immunogen
Recombinant Complement Component 4 (Asn975~Arg1336) expressed in E.coli.
Target
Non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. C4A isotype is responsible for effective binding to form amide bonds with immune aggregates or protein antigens, while C4B isotype catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.7 mg/ml
Format
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
188 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against C4. It has been selected for its ability to recognize C4 in immunohistochemical staining and western blotting.
NCBI Gene Symbol
C4A|C4B
Host or Source
Rabbit
Protein Name
Complement C4-A
Gene Name URL
C4A|C4B
Nucleotide Accession Number
NM_001002029
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