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C2CD3 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

C2 domain containing 3 centriole elongation regulator

Gene Aliases

C2 calcium dependent domain containing 3; C2 domain-containing protein 3; OFD14.

Gene ID

26005

Accession Number

NP_001273506.1

Reactivity

Human

Immunogen

Range: Asn1432 - Leu1647

Target

Component of the centrioles that acts as a positive regulator of centriole elongation (PubMed:24997988) . Promotes assembly of centriolar distal appendage, a structure at the distal end of the mother centriole that acts as an anchor of the cilium, and is required for recruitment of centriolar distal appendages proteins CEP83, SCLT1, CEP89, FBF1 and CEP164. Not required for centriolar satellite integrity or RAB8 activation. Required for primary cilium formation (PubMed:23769972) . Required for sonic hedgehog/SHH signaling and for proteolytic processing of GLI3.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

Purification

Affinity Purified; Protein A Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Reconstitution

2°C to 8°C|-20°C

Molecular Weight

210 kDa

Fragment

IgG

Specificity

The antibody is a rabbit polyclonal antibody raised against C2CD3. It has been selected for its ability to recognize C2CD3 in immunohistochemical staining and western blotting.

NCBI Gene Symbol

C2CD3

Host or Source

Rabbit

Protein Name

C2 domain-containing protein 3

Gene Name URL

C2CD3

Nucleotide Accession Number

NM_001286577

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