BACE2 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Beta-site APP-cleaving enzyme 2

Gene Aliases

1110059C24Rik; A; AEPLC; AI850424; AL; ALP56; ARP1; AS; ASP1; ASP21; aspartyl protease 1; BAE; BAE2; beta-secretase 2; beta-site amyloid precursor protein cleaving enzyme 2; CDA1; CDA13; CEA; CEAP1; DRAP; memapsin-1; membrane-associated aspartic protease 1; theta-secretase.

Gene ID

56175

Accession Number

NP_062390.3

Reactivity

Human|Mouse|Rat

Immunogen

Range: Glu156 - Val407

Target

Responsible for the proteolytic processing of the amyloid precursor protein (APP) . Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672 (By similarity) .

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

Purification

Affinity Purified; Protein A Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

Reconstitution

2°C to 8°C|-20°C

Molecular Weight

56 kDa

Fragment

IgG

Specificity

The antibody is a rabbit polyclonal antibody raised against bACE2. It has been selected for its ability to recognize bACE2 in immunohistochemical staining and western blotting.