Icariin
Icariin is a flavonol glycoside. Icariin inhibits PDE5 and PDE4 activities with IC50s of 432 nM and 73.50 μM, respectively. Icariin also is a PPARα activator.
Product Specifications
CAS Number
489-32-7
Product Name Alternative
Ieariline
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Autophagy; Phosphodiesterase (PDE) ; PPAR
Type
Natural Products
Related Pathways
Autophagy; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology; Cardiovascular Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/Icariin.html
Purity
99.06
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O[C@H]1[C@H](O)[C@@H](CO)O[C@@H](OC2=C(C/C=C(C)/C)C(OC(C3=CC=C(OC)C=C3)=C(O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)C5=O)=C5C(O)=C2)[C@@H]1O
Molecular Formula
C33H40O15
Molecular Weight
676.66
Precautions
H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Phase 3
Isoform
PDE4; PDE5; PPARα
Available Sizes
Frequently Asked Questions
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