What is the catalog number for ATG16L1 Antibody?

The catalog number for ATG16L1 Antibody is OACD01842-1ML.

What sizes are available for ATG16L1 Antibody?

ATG16L1 Antibody is available in the following size(s): 1 mL.

Is ATG16L1 Antibody in stock?

ATG16L1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

ATG16L1 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Autophagy related 16 like 1

Gene Aliases

APG16L; APG16L beta; APG16-like 1; ATG16 autophagy related 16-like 1; ATG16A; ATG16L; autophagy-related protein 16-1; IBD10; WD repeat domain 30; WDR30.

Gene ID

55054

Accession Number

NP_001177195.1

Reactivity

Human|Mouse|Porcine|Rat

Immunogen

Range: Met1 - Gly284

Target

Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane (PubMed:24553140, PubMed:23376921, PubMed:24954904, PubMed:27273576, PubMed:23392225) . Regulates mitochondrial antiviral signaling (MAVS) -dependent type I interferon (IFN-I) production (PubMed:25645662) . Negatively regulates NOD1- and NOD2-driven inflammatory cytokine response (PubMed:24238340) . Instead, promotes with NOD2 an autophagy-dependent antibacterial pathway (PubMed:20637199) . Plays a role in regulating morphology and function of Paneth cell (PubMed:18849966) .

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

Purification

Affinity Purified; Protein A Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.98 mg/ml

Format

Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Reconstitution

2°C to 8°C|-20°C

Molecular Weight

48 kDa

Fragment

IgG

Specificity

The antibody is a rabbit polyclonal antibody raised against ATG16L1. It has been selected for its ability to recognize ATG16L1 in immunohistochemical staining and western blotting.