APOO Antibody
Product Specifications
Gene Name
Apolipoprotein O
Gene Aliases
Apolipoprotein O; brain my025; FAM121B; family with sequence similarity 121B; Mic23; MIC26; MICOS complex subunit MIC23; MICOS complex subunit MIC26; MICOS26; mitochondrial contact site and cristae organizing system subunit 26; My025; Protein FAM121B.
Gene ID
79135
Accession Number
NP_077027.1
Reactivity
Human|Mouse|Porcine
Immunogen
Range: Lys26 - Lys198
Target
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a crucial role in crista junction formation and mitochondrial function (PubMed:25764979) . Can promote cardiac lipotoxicity by enhancing mitochondrial respiration and fatty acid metabolism in cardiac myoblasts (PubMed:24743151) . Promotes cholesterol efflux from macrophage cells. Detected in HDL, LDL and VLDL. Secreted by a microsomal triglyceride transfer protein (MTTP) -dependent mechanism, probably as a VLDL-associated protein that is subsequently transferred to HDL (PubMed:16956892) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
20 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against APOO. It has been selected for its ability to recognize APOO in immunohistochemical staining and western blotting.
NCBI Gene Symbol
APOO
Host or Source
Rabbit
Protein Name
MICOS complex subunit MIC26
Gene Name URL
APOO
CAS Number
9007-83-4
Nucleotide Accession Number
NM_024122
Curated Selection
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