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MEF2A Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Myocyte enhancer factor 2A

Gene Aliases

ADCAD1; MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A) ; mef2; myocyte-specific enhancer factor 2A; RSRFC4; RSRFC9; serum response factor-like protein 1.

Gene ID

4205

Accession Number

NP_001124399.1

Reactivity

Human|Mouse|Rat

Immunogen

Range: Met1 - Ser162

Target

Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT] (4) TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

Purification

Affinity Purified; Protein A Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

Reconstitution

2°C to 8°C|-20°C

Molecular Weight

46 kDa

Fragment

IgG

Specificity

The antibody is a rabbit polyclonal antibody raised against MEF2A. It has been selected for its ability to recognize MEF2A in immunohistochemical staining and western blotting.

NCBI Gene Symbol

MEF2A

Host or Source

Rabbit

Protein Name

Myocyte-specific enhancer factor 2A

Gene Name URL

MEF2A

Nucleotide Accession Number

NM_001130927

Frequently Asked Questions

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