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NCR3 Antibody

Product Specifications

Gene Name

Natural cytotoxicity triggering receptor 3

Gene Aliases

1C7; activating natural killer receptor p30; activating NK-A1 receptor; CD337; LY117; lymphocyte antigen 117; MALS; natural cytotoxicity triggering receptor 3; natural killer cell p30-related protein; NKp30; NK-p30.

Gene ID

259197

Accession Number

NP_001138938.1

Reactivity

Human|Mouse

Immunogen

Range: Ser22 - Gly135

Target

Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG which promote DC maturation.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

Purification

Affinity Purified; Protein A Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

Reconstitution

2°C to 8°C|-20°C

Molecular Weight

16 kDa

Fragment

IgG

Specificity

The antibody is a rabbit polyclonal antibody raised against NCR3. It has been selected for its ability to recognize NCR3 in immunohistochemical staining and western blotting.

NCBI Gene Symbol

NCR3

Host or Source

Rabbit

Protein Name

Natural cytotoxicity triggering receptor 3

Gene Name URL

NCR3

CAS Number

9007-83-4

Nucleotide Accession Number

NM_001145466

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