What is the catalog number for UXT Antibody?

The catalog number for UXT Antibody is OACD01106-100UL.

What sizes are available for UXT Antibody?

UXT Antibody is available in the following size(s): 100 µL.

Is UXT Antibody in stock?

UXT Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

UXT Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Ubiquitously expressed prefoldin like chaperone

Gene Aliases

Androgen receptor trapped clone 27 protein; ART-27; protein UXT; SKP2-associated alpha PFD 1; STAP1; ubiquitously expressed transcript protein.

Gene ID

8409

Accession Number

NP_004173.1

Reactivity

Human|Mouse|Rat

Immunogen

Range: Glu15 - His157

Target

Involved in gene transcription regulation (PubMed:28106301, PubMed:21730289) . Acts in concert with the corepressor URI1 to regulate androgen receptor AR-mediated transcription (PubMed:11854421, PubMed:21730289) . Together with URI1, associates with chromatin to the NKX3-1 promoter region (PubMed:21730289) . Negatively regulates the transcriptional activity of the estrogen receptor ESR1 by inducing its translocation into the cytoplasm (PubMed:28106301) . May act as nuclear chaperone that facilitates the formation of the NF-kappa-B enhanceosome and thus positively regulates NF-kappa-B transcription activity (PubMed:17620405, PubMed:21307340) . Potential component of mitochondrial-associated LRPPRC, a multidomain organizer that potentially integrates mitochondria and the microtubular cytoskeleton with chromosome remodeling (PubMed:17554592) . Increasing concentrations of UXT contributes to progressive aggregation of mitochondria and cell death potentially through its association with LRPPRC (PubMed:17554592) . Suppresses cell transformation and it might mediate this function by interaction and inhibition of the biological activity of cell proliferation and survival stimulatory factors like MECOM (PubMed:17635584) .

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

Purification

Affinity Purified; Protein A Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

Reconstitution

2°C to 8°C|-20°C

Molecular Weight

18 kDa

Fragment

IgG

Specificity

The antibody is a rabbit polyclonal antibody raised against UXT. It has been selected for its ability to recognize UXT in immunohistochemical staining and western blotting.