PLSCR3 Antibody
Product Specifications
Gene Name
Phospholipid scramblase 3
Gene Aliases
2210403O21Rik;2610037N06Rik; Ca 2+ dependent phospholipid scramblase 3; ca (2+) -dependent phospholipid scramblase 3; ESTM3; phospholipid scramblase 3; PL scramblase 3; X83310.
Gene ID
70310
Accession Number
NP_001161969.1
Reactivity
Human|Mouse|Rat
Immunogen
Range: Leu99 - Asp253
Target
May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
32 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against PLSCR3. It has been selected for its ability to recognize PLSCR3 in immunohistochemical staining and western blotting.
NCBI Gene Symbol
Plscr3
Host or Source
Rabbit
Protein Name
Phospholipid scramblase 3
Gene Name URL
Plscr3
CAS Number
9007-83-4
Nucleotide Accession Number
NM_001168497
Curated Selection
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