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TFB2M Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Transcription factor B2, mitochondrial

Gene Aliases

Dimethyladenosine transferase 2, mitochondrial; HCV NS5A-transactivated protein 5; hepatitis C virus NS5A-transactivated protein 5; Hkp1; h-mtTFB; h-mtTFB2; hTFB2M; mitochondrial 12S rRNA dimethylase 2; mitochondrial transcription factor B2; mtTFB2; S-adenosylmethionine-6-N', N'-adenosyl (rRNA) dimethyltransferase 2.

Gene ID

64216

Accession Number

NP_071761

Reactivity

Human

Immunogen

Recombinant Human Dimethyladenosine transferase 2, mitochondrial protein (30-108AA)

Target

S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunohistochemistry

Purification

Protein G Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Format

Liquid

Reconstitution

-20°C or -80°C

Fragment

IgG

NCBI Gene Symbol

TFB2M

Host or Source

Rabbit

Protein Name

Dimethyladenosine transferase 2, mitochondrial

Gene Name URL

TFB2M

Nucleotide Accession Number

NM_022366

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