MBD3 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Methyl-CpG binding domain protein 3

Gene Aliases

Methyl-CpG-binding domain protein 3; Methyl-CpG-binding protein MBD3.

Gene ID

53615

Accession Number

NP_001268382

Reactivity

Human|Mouse

Immunogen

Recombinant Human Methyl-CpG-binding domain protein 3 protein (79-209AA)

Target

Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself (PubMed:12124384) . Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro) . Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (PubMed:24307175) . Recruits histone deacetylases and DNA methyltransferases.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot

Purification

Protein G Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol