GRIN2C Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Glutamate ionotropic receptor NMDA type subunit 2C
Gene Aliases
GluN2C; GluN2C (alt_5'UTR_77nt) ; GluN2C (alt_5'UTR_87nt) ; GluN2C (del_e2) ; glutamate [NMDA] receptor subunit epsilon-3; glutamate receptor ionotropic, NMDA 2C; glutamate receptor, ionotropic, N-methyl D-aspartate 2C; NMDAR2C; N-methyl D-aspartate receptor subtype 2C; N-methyl-D-aspartate receptor subunit 2C; NR2C; putative NMDtranscript (altAcc_e11) ; putative NMDtranscript (altDon_e4) ; putative NMDtranscript (del_e4) .
Gene ID
2905
Accession Number
NP_000826
Reactivity
Human
Immunogen
Recombinant Human Glutamate receptor ionotropic, NMDA 2C protein (908-1007AA)
Target
Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg (2+) (PubMed:26875626) . Sensitivity to glutamate and channel kinetics depend on the subunit composition (Probable) . Plays a role in regulating the balance between excitatory and inhibitory activity of pyramidal neurons in the prefrontal cortex. Contributes to the slow phase of excitatory postsynaptic current, long-term synaptic potentiation, and learning (By similarity) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
GRIN2C
Host or Source
Rabbit
Protein Name
Glutamate receptor ionotropic, NMDA 2C
Gene Name URL
GRIN2C
Nucleotide Accession Number
NM_000835
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