IER3 Antibody
Product Specifications
Gene Name
Immediate early response 3
Gene Aliases
Anti-death protein; DIF2; DIF-2; differentiation-dependent gene 2 protein; expressed in pancreatic carcinoma; GLY96; gly96, mouse, homolog of; IEX1; IEX-1; IEX-1L; immediate early protein GLY96; immediate early response 3 protein; immediately early gene X-1; PACAP-responsive gene 1 protein; PRG1; protein DIF-2; radiation-inducible immediate-early gene IEX-1.
Gene ID
8870
Accession Number
NP_003888
Reactivity
Human
Immunogen
Recombinant Human Radiation-inducible immediate-early gene IEX-1 protein (1-82AA)
Target
May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
IER3
Host or Source
Rabbit
Protein Name
Radiation-inducible immediate-early gene IEX-1
Gene Name URL
IER3
CAS Number
9007-83-4
Nucleotide Accession Number
NM_003897
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