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RYR2 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Ryanodine receptor 2

Gene Aliases

ARVC2; ARVD2; Cardiac muscle ryanodine receptor; cardiac muscle ryanodine receptor-calcium release channel; cardiac-type ryanodine receptor; islet-type ryanodine receptor; kidney-type ryanodine receptor; ryanodine receptor 2; ryanodine receptor 2 (cardiac) ; RyR; RYR-2; type 2 ryanodine receptor; VACRDS; VTSIP.

Gene ID

6262

Accession Number

NP_001026

Reactivity

Human

Immunogen

Recombinant Human Ryanodine receptor 2 protein (901-1192AA)

Target

Calcium channel that mediates the release of Ca (2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca (2+) levels due to activation of the L-type calcium channel CACNA1C. The calcium channel activity is modulated by formation of heterotetramers with RYR3. Required for cellular calcium ion homeostasis. Required for embryonic heart development.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry

Purification

Protein G Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Format

Liquid

Reconstitution

-20°C or -80°C

Fragment

IgG

NCBI Gene Symbol

RYR2

Host or Source

Rabbit

Protein Name

Ryanodine receptor 2

Gene Name URL

RYR2

Nucleotide Accession Number

NM_001035

Frequently Asked Questions

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