RANBP1 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
RAN binding protein 1
Gene Aliases
HpaII tiny fragments locus 9A; HTF9A; Ran-binding protein 1; ran-specific GTPase-activating protein; testis secretory sperm-binding protein Li 221n.
Gene ID
5902
Accession Number
NP_001265568
Reactivity
Human
Immunogen
Recombinant Human Ran-specific GTPase-activating protein (52-111AA)
Target
Plays a role in RAN-dependent nucleocytoplasmic transport. Alleviates the TNPO1-dependent inhibition of RAN GTPase activity and mediates the dissociation of RAN from proteins involved in transport into the nucleus (By similarity) . Induces a conformation change in the complex formed by XPO1 and RAN that triggers the release of the nuclear export signal of cargo proteins (PubMed:20485264) . Promotes the disassembly of the complex formed by RAN and importin beta. Promotes dissociation of RAN from a complex with KPNA2 and CSE1L (By similarity) . Required for normal mitotic spindle assembly and normal progress through mitosis via its effect on RAN (PubMed:17671426) . Does not increase the RAN GTPase activity by itself, but increases GTP hydrolysis mediated by RANGAP1 (PubMed:7882974) . Inhibits RCC1-dependent exchange of RAN-bound GDP by GTP (PubMed:7882974, PubMed:7616957) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
RANBP1
Host or Source
Rabbit
Protein Name
Ran-specific GTPase-activating protein
Gene Name URL
RANBP1
Nucleotide Accession Number
NM_001278639
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
SA4810 1008 Pack (72 Label x 14 Card)
TERMINAL BLOCK TAG, AB, 6x9-6 Rigid Wire and Panel Tags for Printers
Ask
View Details 
MBS1044896-01 0.02 mg (E-Coli)
Recombinant Bacillus subtilis Uncharacterized protein yukE (yukE)
Ask
View Details MBS1044896-02 0.1 mg (E-Coli)
Recombinant Bacillus subtilis Uncharacterized protein yukE (yukE)
Ask
View Details MBS1044896-03 0.02 mg (Yeast)
Recombinant Bacillus subtilis Uncharacterized protein yukE (yukE)
Ask
View Details 
MBS1044896-04 0.1 mg (Yeast)
Recombinant Bacillus subtilis Uncharacterized protein yukE (yukE)
Ask
View Details MBS1044896-05 0.02 mg (Baculovirus)
Recombinant Bacillus subtilis Uncharacterized protein yukE (yukE)
Ask
View Details