NDC80 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
NDC80 kinetochore complex component
Gene Aliases
HEC; HEC1; highly expressed in cancer protein; highly expressed in cancer, rich in leucine heptad repeats; HsHec1; hsNDC80; kinetochore associated 2; kinetochore protein Hec1; kinetochore protein NDC80 homolog; kinetochore-associated protein 2; KNTC2; NDC80 homolog, kinetochore complex component; NDC80 kinetochore complex component homolog; retinoblastoma-associated protein HEC; TID3.
Gene ID
10403
Accession Number
NP_006092
Reactivity
Human
Immunogen
Recombinant Human Kinetochore protein NDC80 homolog protein (1-249AA)
Target
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:9315664, PubMed:12351790, PubMed:14654001, PubMed:14699129, PubMed:15062103, PubMed:15235793, PubMed:15239953, PubMed:15548592, PubMed:16732327) . Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (PubMed:15548592) . The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules (PubMed:23085020) . Plays a role in chromosome congression and is essential for the end-on attachment of the kinetochores to spindle microtubules (PubMed:25743205, PubMed:23891108) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
NDC80
Host or Source
Rabbit
Protein Name
Kinetochore protein NDC80 homolog
Gene Name URL
NDC80
Nucleotide Accession Number
NM_006101
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7057213-01 0.02 mg (E-Coli)
Recombinant Human Synaptic vesicle glycoprotein 2C (SV2C), partial
Ask
View Details MBS7057213-02 0.1 mg (E-Coli)
Recombinant Human Synaptic vesicle glycoprotein 2C (SV2C), partial
Ask
View Details MBS7057213-03 0.02 mg (Yeast)
Recombinant Human Synaptic vesicle glycoprotein 2C (SV2C), partial
Ask
View Details MBS7057213-04 0.1 mg (Yeast)
Recombinant Human Synaptic vesicle glycoprotein 2C (SV2C), partial
Ask
View Details 
MBS7057213-05 0.02 mg (Baculovirus)
Recombinant Human Synaptic vesicle glycoprotein 2C (SV2C), partial
Ask
View Details MBS7057213-06 0.02 mg (Mammalian-Cell)
Recombinant Human Synaptic vesicle glycoprotein 2C (SV2C), partial
Ask
View Details