ADGRB1 Antibody
Product Specifications
Gene Name
Adhesion G protein-coupled receptor B1
Gene Aliases
Adhesion G protein-coupled receptor B1; BAI1; brain-specific angiogenesis inhibitor 1; GDAIF.
Gene ID
575
Accession Number
NP_001693
Reactivity
Human
Immunogen
Recombinant Human Adhesion G protein-coupled receptor B1 protein (60-350AA)
Target
Phosphatidylserine receptor which enhances the engulfment of apoptotic cells (PubMed:24509909) . Also mediates the binding and engulfment of Gram-negative bacteria (PubMed:26838550) . Stimulates production of reactive oxygen species by macrophages in response to Gram-negative bacteria, resulting in enhanced microbicidal macrophage activity (PubMed:26838550) . In the gastric mucosa, required for recognition and engulfment of apoptotic gastric epithelial cells (PubMed:24509909) . Promotes myoblast fusion (By similarity) . Activates the Rho pathway in a G-protein-dependent manner (PubMed:23782696) . Inhibits MDM2-mediated ubiquitination and degradation of DLG4/PSD95, promoting DLG4 stability and regulating synaptic plasticity (By similarity) . Required for the formation of dendritic spines by ensuring the correct localization of PARD3 and TIAM1 (By similarity) . Potent inhibitor of angiogenesis in brain and may play a significant role as a mediator of the p53/TP53 signal in suppression of glioblastoma (PubMed:11875720) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
ADGRB1
Host or Source
Rabbit
Protein Name
Adhesion G protein-coupled receptor B1
Gene Name URL
ADGRB1
CAS Number
9007-83-4
Nucleotide Accession Number
NM_001702
Curated Selection
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