CD320 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
CD320 molecule
Gene Aliases
8D6;8D6 antigen;8D6A; CD320 antigen; FDC-signaling molecule 8D6; FDC-SM-8D6; TCBLR; TCN2R; transcobalamin 2 receptor; transcobalamin receptor.
Gene ID
51293
Accession Number
NP_001159367
Reactivity
Human
Immunogen
Recombinant Human CD320 antigen protein (36-229AA)
Target
Receptor for transcobalamin saturated with cobalamin (TCbl) (PubMed:18779389) . Plays an important role in cobalamin uptake (PubMed:18779389, PubMed:20524213) . Plasma membrane protein that is expressed on follicular dendritic cells (FDC) and mediates interaction with germinal center B cells (PubMed:10727470) . Functions as costimulator to promote B cell responses to antigenic stimuli; promotes B cell differentiation and proliferation (PubMed:10727470, PubMed:11418631) . Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC) (PubMed:11418631) . CD320 augments the proliferation of PC precursors generated by IL-10 (PubMed:11418631) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
CD320
Host or Source
Rabbit
Protein Name
CD320 antigen
Gene Name URL
CD320
Nucleotide Accession Number
NM_001165895
Curated Selection
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