DSTYK Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Dual serine/threonine and tyrosine protein kinase

Gene Aliases

CAKUT1; dual serine/threonine and tyrosine protein kinase; dusty PK; dusty protein kinase; DustyPK; HDCMD38P; receptor-interacting serine/threonine-protein kinase 5; RIP5; RIP-homologous kinase; RIPK5; sgK496; spastic paraplegia 23 (autosomal recessive) ; SPG23; sugen kinase 496.

Gene ID

25778

Accession Number

NP_056190

Reactivity

Human

Immunogen

Recombinant Human Dual serine/threonine and tyrosine protein kinase protein (680-929AA)

Target

Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation (PubMed:23862974, PubMed:28157540) . Involved in the regulation of both caspase-dependent apoptosis and caspase-independent cell death (PubMed:15178406) . In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types (PubMed:28157540) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunohistochemistry

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol