ZBTB48 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Zinc finger and BTB domain containing 48
Gene Aliases
GLI-Kruppel family member HKR3; HKR3; krueppel-related zinc finger protein 3; pp9964; telomere zinc finger-associated protein; telomeric zinc finger-associated protein; TZAP; zinc finger and BTB domain-containing protein 48; zinc finger protein 855; ZNF855.
Gene ID
3104
Accession Number
NP_001265576
Reactivity
Human
Immunogen
Recombinant Human Telomere zinc finger-associated protein (1-280AA)
Target
Telomere-binding protein that acts as a regulator of telomere length (PubMed:28500257, PubMed:28082411) . Directly binds the telomeric double-stranded 5'-TTAGGG-3' repeat (PubMed:28500257, PubMed:28082411) . Preferentially binds to telomeres that have a low concentration of shelterin complex and acts as a regulator of telomere length by initiating telomere trimming, a process that prevents the accumulation of aberrantly long telomeres (PubMed:28082411) . Also acts as a transcription regulator that binds to promoter regions (PubMed:7969177, PubMed:24382891, PubMed:28500257) . Regulates expression of a small subset of genes, including MTFP1 (PubMed:28500257) . Regulates expression the J and/or S elements in MHC II promoter (PubMed:7969177) . Acts as a negative regulator of cell proliferation by specifically activating expression of ARF, a tumor suppressor isoform of CDKN2A (PubMed:24382891) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
ZBTB48
Host or Source
Rabbit
Protein Name
Telomere zinc finger-associated protein
Gene Name URL
ZBTB48
Nucleotide Accession Number
NM_001278647
Frequently Asked Questions
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