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RASSF5 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Ras association domain family member 5

Gene Aliases

Maxp1; new ras effector 1; NORE1; NORE1A; NORE1B; novel Ras effector 1; Rap1-binding protein; RAPL; Ras association (RalGDS/AF-6) domain family 5; Ras association (RalGDS/AF-6) domain family member 5; ras association domain-containing protein 5; Ras effector-like protein; RASSF3; regulator for cell adhesion and polarization enriched in lymphoid tissue; Regulator for cell adhesion and polarization enriched in lymphoid tissues; tumor suppressor RASSF3.

Gene ID

83593

Accession Number

NP_872604

Reactivity

Human

Immunogen

Recombinant Human Ras association domain-containing protein 5 protein (1-265AA)

Target

Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. May be involved in regulation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS and KRAS induced apoptosis.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Format

Liquid

Reconstitution

-20°C or -80°C

Fragment

IgG

NCBI Gene Symbol

RASSF5

Host or Source

Rabbit

Protein Name

Ras association domain-containing protein 5

Gene Name URL

RASSF5

Nucleotide Accession Number

NM_182663

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