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IL31RA Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Interleukin 31 receptor A

Gene Aliases

Class I cytokine receptor; CRL; CRL3; cytokine receptor-like 3; GLMR; GLM-R; gp130-like monocyte receptor; GPL; hGLM-R; IL-31 receptor subunit alpha; IL-31R subunit alpha; IL-31RA; interleukin-31 receptor subunit alpha; PLCA2; PRO21384; soluble type I cytokine receptor CRL3; zcytoR17.

Gene ID

133396

Accession Number

NP_001229565

Reactivity

Human

Immunogen

Recombinant Human Interleukin-31 receptor subunit alpha protein (1-300AA)

Target

Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5 (PubMed:11877449, PubMed:14504285, PubMed:15627637, PubMed:15194700) . May function in skin immunity (PubMed:15184896) . Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1 (By similarity) . Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro (By similarity) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunohistochemistry

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Format

Liquid

Reconstitution

-20°C or -80°C

Fragment

IgG

NCBI Gene Symbol

IL31RA

Host or Source

Rabbit

Protein Name

Interleukin-31 receptor subunit alpha

Gene Name URL

IL31RA

Nucleotide Accession Number

NM_001242636

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